Russian Medical Development: News

Any adverse reaction and the western media will go apeshit, but at the end of the day there are people that have adverse reactions... I mean there are people allergic to peanuts and dairy products and lots of other things...

All I can hope is that the people who complain and whine are the last to get the vaccine, but that is not fair to Americans who are not arse holes.

It is a bit like the Soccer World Cup in Russia... despite all the scaremongering by western media, the people who actually went seem to have had a good time... when they got home to their loved ones and told them there was no skin head army there to beat them up every day of their trip, perhaps a few more people in the west might realise... both sides of the story CNN, and the full picture BBC really don't live up to their claims of balance and news.

You would think with the number of dead in the west due to this virus they would be pleased at the news that a vaccine is entering third stage clinical trials....

Russia to supply over 2 mln doses of Sputnik V vaccine to Kazakhstan

The Russian Direct Investment Fund will consider an opportunity of increasing vaccine deliveries to 5 mln doses later on

MOSCOW, August 26. /TASS/. Russia will supply over 2 mln doses of the Sputnik V coronavirus vaccine to Kazakhstan, with an option of further increase to 5 mln doses, chief executive of the Russian Direct Investment Fund (RDIF) Kirill Dmitriev told reporters on Wednesday.

"The agreement stipulates the supply of more than 2 mln doses of the Russian Sputnik-V vaccine to Kazakhstan; we will consider an opportunity of increasing vaccine deliveries to 5 mln doses later on together with partners," Dmitriev said.

RDIF and Kazakhstan-based SK-Pharmacy earlier negotiated supplies of the Russian coronavirus vaccine to the republic.

On August 11, Russia became the first country across the globe that registered a vaccine against the coronavirus infection, named Sputnik V. The pharmaceutical underwent clinical trials in July.

https://tass.com/economy/1193933

Scientists publish results of first two phases of Sputnik V clinical trials

Overall, both vaccine formulations turned out to be approximately equally effective causing all volunteers to develop antibodies to the coronavirus and teaching T-cells to recognize this threat

MOSCOW, September 4. /TASS/. Russian scientists presented preliminary results of the first two phases of clinical trials of two different forms of the Sputnik V vaccine on 76 volunteers which confirmed that both forms of the vaccine are safe for humans and stimulate their immune system to develop antibodies to SARS-CoV-2. The study results were published in the Lancet journal.

"These data collectively show that the heterologous vaccine based on rAd26-S and rAd5-S is safe, well tolerated, and does not cause serious adverse events in healthy adult volunteers. The vaccine is highly immunogenic and induces strong humoral and cellular immune responses in 100% of healthy adult volunteers, with antibody titres in vaccinated participants higher than those in convalescent plasma," the researchers wrote.

On August 11, Russia became the first worldwide to register the vaccine against the coronavirus which was named Sputnik V. The preparation was developed by the Gamaleya National Research Center and passed clinical trials in June - July. It is based on a known platform previously used for other vaccines. On August 15, the Healthcare Ministry announced the production launch of the preparation. The third post-registration phase of clinical trials of the vaccine began on August 25.

Russian vaccine consists of two components based on two different strains of adenovirus, rAd26-S и rAd5-S. The researchers weakened those pathogens and modified their genomes in such a way so that they deliver the coronavirus RNA fragments to human cells, forcing them to produce a large amount of its membrane proteins. These molecules infiltrate immune cells making them produce antibodies to SARS-CoV-2.

"To form a powerful immune response against SARS-CoV-2, it is important that a booster vaccination is provided. However, booster vaccinations that use the same adenovirus vector might not produce an effective response because the immune system may recognize and attack the vector. <…> For our vaccine, we use two different adenovirus vectors in a bid to avoid the immune system becoming immune to the vector," one of the authors of the article, Deputy Research Director at the Gamaleya National Research Center for Epidemiology and Microbiology Denis Logunov said.

According to the researchers, clinical trials of a vaccine were conducted using two different variants of Sputnik V. Some volunteers received injections of rAd26-S and rAd5-S cultures which were stored in a frozen form and others were vaccinated with a freeze-dried form of a vaccine. The booster shots were administered approximately five days after the first injection. The frozen vaccine was tested at one of the branches of the Burdenko Military Hospital, while the freeze-dried one was tested in the clinic of the Sechenov University.

As subsequent observations demonstrated, both adenoviruses and both vaccine formulations were equally safe for the volunteers. They elicited a number of mild side effects, such as pain at injection site or elevated body temperature but over 42 days of trials the researchers have registered no potentially life-threatening complications.

Overall, both vaccine formulations turned out to be approximately equally effective causing all volunteers to develop antibodies to the coronavirus and teaching T-cells to recognize this threat. According to the scientists, the booster dose has elevated significantly the effectiveness of the Sputnik V vaccine, since after a single injection the antibodies were developed in only 60% of volunteers.

The researchers hope that the vaccine developed by them will be equally successful during larger-scale clinical trials approved on August 26. Over 40,000 volunteers of all age groups will participate in them.

https://tass.com/science/1197429

https://www.rt.com/russia/499876-the-lancet-russian-sputnik-vaccine-effectiveness/

It seems professional health journals in the UK are not as closed minded as their politicians....

https://www.rt.com/russia/499949-covid19-vaccine-effective-vaccination-new-year/

There is a difference between being closed-minded and asking fair questions.

Etc Russia declaring the vaccine fit for use without conducting stage 3 mass testing which takes months.

Does make it fair for people to ask "but is it really safe?"

Just learned on the Australian Sky News network that Australia has the first effective vaccine and they will start giving it to people in January 2021... no mention was made about risks, or potential problems... no mention was made of any other vaccines being made anywhere else either... makes all the Aussies proud for this great achievement in being first...

The Russians based their new vaccine on the work they had just completed on SARS which is rather similar so a lot of the work had already been done, but obviously it is a Russian bio warfare tactic they will produce it for themselves and that proves they made the disease in the first place and when they are all immune and the west sees that the west will ask for some and the Russians will give them a special version that turns you into a compliant robot... you know... the stuff the US and UK have been giving to their free media for the last two decades...

It is a plot... don't fall for it...

My point is Russia skipping a required part of the testing process, to rush the vaccine out without the proper data to show or supports its safety or effectiveness makes it a fair and valid criticism for people to ask "Well is it safe? what what could happen".

Russia didn't skip anything. They were already working on a closely related disease and so a lot of the normal tests and procedures could be done in parallel instead of one after the other.

It would be one thing if the Russians had such data to show and support it but they do not, so people acting like "How dare people question Russia's vaccine" is ignorant on their part.

If you read the links I posted from the Lancet... a British medical journal said they had analysed the data and information and it all looked good.

You seem to be confusing the Russians with the British and the Germans who wont reveal data for the Skrypals and Navalny, despite demanding action.