GarryB wrote:Quite a few countries wanting Sputnik V will also want to produce them for themselves so that will boost production too.
It is supposed to be quite straight forward to produce, not requiring brand new untested technology like some of the other vaccines, so the production base can be made much wider and including poorer countries which can get involved in production too.
And since it uses the natural infection immune response instead of GMO attack on every tissue in the body (including the brain),
it is vastly superior to those "bleeding edge technology" wonders. The adenovirus is a routine infection for humans. Including
SARS-Cov-2 proteins in these viruses does the job perfectly. Encasing mRNA in a lipid nanoparticle is Loony Tunes "medicine".
Hijacking cells in every cubic millimeter of the body is gratuitous excess. Now that I think about it, exposing the brain is just
insane. And the brain is exposed because the lipid nanoparticle used as a vector for the mRNA cannot be assured to be
large enough not to cross the blood-brain barrier. There is no cell wall holding this lipid particle together. And hydrophobic
effects are not enough to maintain mechanical cohesion. As these lipid particles get transported in the blood stream, some
of them may well break up with the mRNA retaining the most, but reduced lipid envelope mass. I am also sure that during
the injection process this happens already so what is introduced into the blood stream is not a single-size lipid particle
set but a distribution.