Coronavirus pandemic 2019-20 #4

How many children died from flu during the 2017-2018 season?

As of April 19, 2019, a total of 186 pediatric deaths had been reported to CDC during the 2017-2018 season. This number exceeds the previously highest number of flu-associated deaths in children reported during a regular flu season (171 during the 2012-2013 season). Approximately 80% of these deaths occurred in children who had not received a flu vaccination this season. For the most recent data and more information visit FluView: Influenza-Associated Pediatric Mortality.

Since flu-associated deaths in children became a nationally notifiable condition in 2004, the total number of flu-associated deaths among children during one season has ranged from 37 (during the 2011-2012 season) to 186 (during the 2017-18 season, as of April 19, 2019); this excludes the 2009 pandemic, when 358 pediatric deaths from April 15, 2009 through October 2, 2010 were reported to CDC.

Healthy boys may be more likely to be admitted to hospital with a rare side-effect of the Pfizer/BioNTech Covid vaccine that causes inflammation of the heart than with Covid itself, US researchers claim.

Their analysis of medical data suggests that boys aged 12 to 15, with no underlying medical conditions, are four to six times more likely to be diagnosed with vaccine-related myocarditis than ending up in hospital with Covid over a four-month period.

higurashihougi wrote:https://www.scmp.com/news/china/science/article/3154568/zero-covid-still-less-costly-living-it-chinas-top-expert-zhong

Zero Covid still less costly than living with it, China’s top expert Zhong Nanshan says

China’s top respiratory diseases expert has defended the country’s zero-Covid strategy against scrutiny from some public health experts, saying it was still less costly than living with the disease and reintroducing restrictions each time outbreaks occurred.

The country had no option but to aim for zero infections because the coronavirus was replicating quickly and the global death rate of about 2 per cent was unacceptable, Zhong Nanshan said in an interview with CGTN, China’s state-owned international media arm, published late on Monday.

“Some countries have decided to open up entirely despite still having a few infections,” Zhong said. “That led to a large number of infections in the past two months and they decided to reimpose restrictions. This flip-flopping approach is actually more costly. The psychological impact on citizens and society is greater.”

JohninMK wrote:If you really want to get worried watch Mike Adams report yesterday where he describes what a couple of researchers in Sweden seem to have found that the spike protein does.

Warning, you can't unwatch this.

https://www.brighteon.com/cb351cd3-6c94-4f2b-a05d-bbda757d4472

If it is correct it is a good explanation as to what is going on, in particular huge numbers of people going into hospital in the US.

As per https://www.zerohedge.com/medical/something-really-strange-happening-hospitals-all-over-america

Do not expect much in the MSN on this.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led
to the coronavirus disease 2019 (COVID-19) pandemic, severely affecting public
health and the global economy. Adaptive immunity plays a crucial role in fighting
against SARS-CoV-2 infection and directly influences the clinical outcomes of patients.
Clinical studies have indicated that patients with severe COVID-19 exhibit delayed and
weak adaptive immune responses; however, the mechanism by which SARS-CoV-2
impedes adaptive immunity remains unclear. Here, by using an in vitro cell line, we
report that the SARS-CoV-2 spike protein significantly inhibits DNA damage repair,
which is required for effective V(D)J recombination in adaptive immunity. Mechanistically,
we found that the spike protein localizes in the nucleus and inhibits DNA damage repair
by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site.
Our findings reveal a potential molecular mechanism by which the spike protein might
impede adaptive immunity and underscore the potential side effects of full-length
spike-based vaccines.

As two critical host surveillance systems, the immune and DNA repair systems are
the primary systems that higher organisms rely on for defense against diverse threats and
tissue homeostasis. Emerging evidence indicates that these two systems are interdependent,
especially during lymphocyte development and maturation [7]. As one of the major double-
strand DNA break (DSB) repair pathways, non-homologous end joining (NHEJ) repair
plays a critical role in lymphocyte–specific recombination–activating gene endonuclease
(RAG) –mediated V(D)J recombination, which results in a highly diverse repertoire of
antibodies in B cell and T cell receptors (TCRs) in T cells [8]. For example, loss of function
of key DNA repair proteins such as ATM, DNA–PKcs, 53BP1, et al., leads to defects
in the NHEJ repair which inhibit the production of functional B and T cells, leading to
immunodeficiency [7,9–11]. In contrast, viral infection usually induces DNA damage via
different mechanisms, such as inducing reactive oxygen species (ROS) production and
host cell replication stress [12–14]. If DNA damage cannot be properly repaired, it will
contribute to the amplification of viral infection-induced pathology. Therefore, we aimed to
investigate whether SARS–CoV–2 proteins hijack the DNA damage repair system, thereby
affecting adaptive immunity in vitro.

There’s been a serious terminology problem with this issue. The problem, of course, is not “immune enhancement,” which
sounds like something helpful to the immune system. In fact, it is quite the opposite. The problem is, in reality “disease enhancement”;
in fact, that is what it was called in the original RSV study. Disease enhancement now appears to be caused by initial exposure to a
pathogen’s proteins, or parts of proteins, which primes the body to autoimmunity. That is “pathogenic priming.” In COVID-19, every
protein in the SARS-CoV-2 has at least one epitope that matches human proteins someplace in the human body. About one-third
of the epitopes in SARS-CoV-2 virus that match human proteins match immune system proteins.