We can assume that the Su-25s are, as well as being directed at known pre-determined targets, probably being Forward Air Controlled by either embedded Russian advisers or SAA specialists as well, it is too sensible not to do it.
If US/NATO may use them just as a 5000m bomb carrier like the Su-24. But what if they are going to use them in both roles as well, where will the FAC be? No problem with Kurds vs ISIS, but say where the SAA is fighting ISIS or even Nusra vs ISIS. Whereas an F-16 would merge in with many other similar shaped aircraft the A-10 sticks out as a definite video opportunity. If a Stinger rises out of a crowded battlefield and hits one, who fired it will be difficult to prove.
I don't think I have put it very well but this could be about to get very nasty.