When we start going to other places like the Moon and Mars things become much more work and more expensive and more complicated.
The more we learn to reuse and recycle on Mars, perhaps the more efficiently we will be able to use resources on Earth and reduce pollution and waste and the damage we do.
The moons of the large planets are interesting... especially that ice covered one that supposedly has vast oceans of water under the ice surface... but the low temperatures, extreme tidal gravitation forces and of course radiation from the large planets makes things difficult... likely robots first.
Talk of sending people to Saturns moons when the Sun expands just because it has a thick atmosphere ignores the fact that it has a thick atmosphere because it is so cold... heat it up with an enlarged sun and most of that thick atmosphere will just blow away... and you get left with little to no atmosphere at all... it would be more efficient going to the ice covered moon but what would be its fate when heated up... melting ice and loss of water to become a dry atmosphere-less rock.